After making her acting debut in the comedy film Fugly (2014), she played MS Dhoni's wife in the sports biopic M.S. Dhoni: The Untold Story (2016).

She gained praise for playing a sexually unsatisfied wife in the Netflix anthology film Lust Stories (2018) and played the leading lady in the political thriller Bharat Ane Nenu (2018)

Advani received wider attention for starring in the romantic drama Kabir Singh and the comedy Good Newwz, two of the highest-grossing Hindi films of 2019.

This success continued with her roles in the films Shershaah (2021), Bhool Bhulaiyaa 2 (2022) and Jugjugg Jeeyo (2022).

Advani began her acting career with the Hindi ensemble comedy film Fugly (2014)

Taran Adarsh of Bollywood Hungama wrote, "Kiara Advani catches you completely unaware" and has the "combination of looks and talent".

Mehul S Thakkar of Deccan Chronicle found her "very striking" and said that she "shows a lot of promise".

Advani expanded to Telugu cinema that year, appearing with Mahesh Babu in the action film Bharat Ane Nenu (2018) from Koratala Siva, about a student who unexpectedly becomes chief minister of Andhra Pradesh

Advani received wider attention later in 2019 for Sandeep Reddy Vanga's romantic drama Kabir Singh, starring Shahid Kapoor.